Surfactant delivery techniques

Selective bronchial instillation

• Using a conventional tube

• Using a double lumen tube

• Via a bronchoscope

Advantages

• Delivers large doses to distal regions of lung

• Reduces dose (costs)

Disadvantages

• Complexity of procedures

• Long time treatment

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Selective bronchial instillation of surfactant has been suggested using a conventional tube introduced in one main bronchus or using a bilumen tube or via a bronchoscope. The advantages deriving from these methods are the delivery of large doses to distal regions of lung and the reduction of the total amount of dose instilled (cost reduction) . The disadvantages of these methods are connected with the complexity of procedures.

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